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Competitive antagonism of fluorescent gentamicin uptake in the cochlea
Aminoglycosides enter inner ear hair cells via apical endocytosis, or mechanoelectrical transduction channels, implying that, in vivo, aminoglycosides enter hair cells from endolymph prior to exerting their cytotoxic effect. If so, circulating aminoglycosides likely cross the strial blood-labyrinth...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923250/ https://ncbi.nlm.nih.gov/pubmed/20561573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2010.06.008 |
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