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Acoustic Trauma Increases Cochlear and Hair Cell Uptake of Gentamicin

BACKGROUND: Exposure to intense sound or high doses of aminoglycoside antibiotics can increase hearing thresholds, induce cochlear dysfunction, disrupt hair cell morphology and promote hair cell death, leading to permanent hearing loss. When the two insults are combined, synergistic ototoxicity occu...

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書誌詳細
主要な著者: Li, Hongzhe, Wang, Qi, Steyger, Peter S.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084257/
https://ncbi.nlm.nih.gov/pubmed/21552569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019130
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