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Trafficking of Systemic Fluorescent Gentamicin into the Cochlea and Hair Cells
Aminoglycosides enter inner ear hair cells across their apical membranes via endocytosis, or through the mechanoelectrical transduction channels in vitro, suggesting that these drugs enter cochlear hair cells from endolymph to exert their cytotoxic effect. We used zebrafish to determine if fluoresce...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674203/ https://ncbi.nlm.nih.gov/pubmed/19255807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-009-0160-4 |
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