Uptake of Fluorescent Gentamicin by Peripheral Vestibular Cells after Systemic Administration

OBJECTIVE: In addition to cochleotoxicity, systemic aminoglycoside pharmacotherapy causes vestibulotoxicity resulting in imbalance and visual dysfunction. The underlying trafficking routes of systemically-administered aminoglycosides from the vasculature to the vestibular sensory hair cells are larg...

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Bibliographic Details
Published in:PLoS One
Main Authors: Liu, Jianping, Kachelmeier, Allan, Dai, Chunfu, Li, Hongzhe, Steyger, Peter S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368668/
https://ncbi.nlm.nih.gov/pubmed/25793391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120612
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