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Combinatorial profiling of chromatin-binding modules reveals multi-site discrimination
Specific interactions between post-translational modifications (PTMs) and chromatin-binding proteins are central to the idea of a ‘histone code’. Here, a 5000-member, PTM-randomized, combinatorial peptide library based on the N-terminus of histone H3 was utilized to interrogate multi-site specificit...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922993/ https://ncbi.nlm.nih.gov/pubmed/20190764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.319 |
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