Combinatorial profiling of chromatin-binding modules reveals multi-site discrimination

Specific interactions between post-translational modifications (PTMs) and chromatin-binding proteins are central to the idea of a ‘histone code’. Here, a 5000-member, PTM-randomized, combinatorial peptide library based on the N-terminus of histone H3 was utilized to interrogate multi-site specificit...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Garske, Adam L., Oliver, Samuel S., Wagner, Elise K., Musselman, Catherine A., LeRoy, Gary, Garcia, Benjamin A., Kutateladze, Tatiana G., Denu, John M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922993/
https://ncbi.nlm.nih.gov/pubmed/20190764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.319
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker