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Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications

CHD4 (chromodomain helicase DNA-binding protein 4) ATPase is a major subunit of the repressive NuRD (nucleosome remodelling and deacetylase) complex, which is involved in transcriptional regulation and development. CHD4 contains two PHD (plant homeodomain) fingers of unknown function. Here we show t...

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Autori principali: MUSSELMAN, Catherine A., MANSFIELD, Robyn E., GARSKE, Adam L., DAVRAZOU, Foteini, KWAN, Ann H., OLIVER, Samuel S., O’LEARY, Heather, DENU, John M., MACKAY, Joel P., KUTATELADZE, Tatiana G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885444/
https://ncbi.nlm.nih.gov/pubmed/19624289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090870
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