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Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

Alzheimer's disease (AD) brains are characterized by amyloid-β-containing plaques and hyperphosphorylated tau-containing neurofibrillary tangles (NFTs); however, in frontotemporal dementia, the tau pathology manifests in the absence of overt amyloid-β plaques. Therapeutic strategies so far have...

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Detalhes bibliográficos
Main Authors: van Eersel, Janet, Ke, Yazi D., Liu, Xin, Delerue, Fabien, Kril, Jillian J., Götz, Jürgen, Ittner, Lars M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922247/
https://ncbi.nlm.nih.gov/pubmed/20643941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009038107
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