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Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models
Alzheimer's disease (AD) brains are characterized by amyloid-β-containing plaques and hyperphosphorylated tau-containing neurofibrillary tangles (NFTs); however, in frontotemporal dementia, the tau pathology manifests in the absence of overt amyloid-β plaques. Therapeutic strategies so far have...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922247/ https://ncbi.nlm.nih.gov/pubmed/20643941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009038107 |
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