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Phosphorylated Tau Interacts with c-Jun N-terminal Kinase-interacting Protein 1 (JIP1) in Alzheimer Disease

In Alzheimer disease (AD) and frontotemporal dementia the microtubule-associated protein Tau becomes progressively hyperphosphorylated, eventually forming aggregates. However, how Tau dysfunction is associated with functional impairment is only partly understood, especially at early stages when Tau...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ittner, Lars M., Ke, Yazi D., Götz, Jürgen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742856/
https://ncbi.nlm.nih.gov/pubmed/19491104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.014472
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