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Tau-Mediated Nuclear Depletion and Cytoplasmic Accumulation of SFPQ in Alzheimer's and Pick's Disease

Tau dysfunction characterizes neurodegenerative diseases such as Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD). Here, we performed an unbiased SAGE (serial analysis of gene expression) of differentially expressed mRNAs in the amygdala of transgenic pR5 mice that express...

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Détails bibliographiques
Auteurs principaux: Ke, Yazi, Dramiga, Joe, Schütz, Ulrich, Kril, Jillian J., Ittner, Lars M., Schröder, Hannsjörg, Götz, Jürgen
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338448/
https://ncbi.nlm.nih.gov/pubmed/22558197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035678
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