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A mutually exclusive alternative exon of slo1 codes for a neuronal BK channel with altered function

Large-conductance Ca(2+)- and voltage-activated K(+) (BK) channels are comprised of four pore-forming α-subunits (Slo1), whose mRNA is alternatively spliced in a cell-specific manner. Here we report the first case of a correctly spliced mutually exclusive exon in a mammalian BK channel; an exon codi...

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Autors principals: Soom, Malle, Gessner, Guido, Heuer, Heike, Hoshi, Toshinori, Heinemann, Stefan H.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921853/
https://ncbi.nlm.nih.gov/pubmed/18719396
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