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Heme Regulates Allosteric Activation of the Slo1 BK Channel

Large conductance calcium-dependent (Slo1 BK) channels are allosterically activated by membrane depolarization and divalent cations, and possess a rich modulatory repertoire. Recently, intracellular heme has been identified as a potent regulator of Slo1 BK channels (Tang, X.D., R. Xu, M.F. Reynolds,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Horrigan, Frank T., Heinemann, Stefan H., Hoshi, Toshinori
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266614/
https://ncbi.nlm.nih.gov/pubmed/15955873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509262
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