Nalaganje...

RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation

The transition from transcription initiation to elongation at the HIV-1 promoter is controlled by Tat, which recruits P-TEFb to TAR RNA to phosphorylate RNA polymerase II. It has long been unclear why the HIV-1 promoter is incompetent for elongation. We report that P-TEFb is recruited to the promote...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: D’Orso, Iván, Frankel, Alan D.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921552/
https://ncbi.nlm.nih.gov/pubmed/20562857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1827
Oznake: Označite
Brez oznak, prvi označite!