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Diazoxide effects on biphasic insulin release: “adrenergic” suppression and enhancement in the perifused rat pancreas

An in vitro system for perifusion of rat pancreas has been used to investigate the effects of diazoxide on glucose-induced insulin release. Administration of diazoxide with a stimulating concentration of glucose produced a dose-dependent suppression of insulin release. This effect was partly reverse...

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Bibliographic Details
Main Authors: Burr, Ian M., Marliss, Errol B., Stauffacher, Werner, Renold, Albert E.
Format: Artigo
Language:Inglês
Published: 1971
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC292083/
https://ncbi.nlm.nih.gov/pubmed/5090060
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