Evidence for the Involvement of Na/Ca Exchange in Glucose-induced Insulin Release from Rat Pancreatic Islets

Glucose-induced inhibition of Ca(++) extrusion from the β-cell may contribute to the rise in cytosol Ca(++) that leads to insulin release. To study whether interference with Na/Ca exchange is involved in this inhibition the effects of glucose were compared to those of ouabain. This substance inhibit...

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Pubblicato in:	J Clin Invest
Autori principali:	Siegel, Eberhard G., Wollheim, Claes B., Renold, Albert E., Sharp, Geoffrey W. G.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1980
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6776149/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109969
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