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Evidence for the Involvement of Na/Ca Exchange in Glucose-induced Insulin Release from Rat Pancreatic Islets

Glucose-induced inhibition of Ca(++) extrusion from the β-cell may contribute to the rise in cytosol Ca(++) that leads to insulin release. To study whether interference with Na/Ca exchange is involved in this inhibition the effects of glucose were compared to those of ouabain. This substance inhibit...

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Détails bibliographiques
Auteurs principaux: Siegel, Eberhard G., Wollheim, Claes B., Renold, Albert E., Sharp, Geoffrey W. G.
Format: Artigo
Langue:Inglês
Publié: 1980
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC371536/
https://ncbi.nlm.nih.gov/pubmed/6776149
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