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Dependency of cyclic AMP-induced insulin release on intra- and extracellular calcium in rat islets of Langerhans.
Calcium and cyclic AMP are important in the stimulation of insulin release. The phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine (IBMX) raises islet cAMP levels and causes insulin release at nonstimulatory glucose concentrations. In isolated rat pancreatic islets maintained for 2 d in tissue...
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| Gepubliceerd in: | J Clin Invest |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Clinical Investigation
1980
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371360/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6153182/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109665 |
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