Diazoxide effects on biphasic insulin release: “adrenergic” suppression and enhancement in the perifused rat pancreas

An in vitro system for perifusion of rat pancreas has been used to investigate the effects of diazoxide on glucose-induced insulin release. Administration of diazoxide with a stimulating concentration of glucose produced a dose-dependent suppression of insulin release. This effect was partly reverse...

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Bibliografische Detailangaben

Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Burr, Ian M., Marliss, Errol B., Stauffacher, Werner, Renold, Albert E.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1971
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292083/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5090060/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106628
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