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Diazoxide effects on biphasic insulin release: “adrenergic” suppression and enhancement in the perifused rat pancreas

An in vitro system for perifusion of rat pancreas has been used to investigate the effects of diazoxide on glucose-induced insulin release. Administration of diazoxide with a stimulating concentration of glucose produced a dose-dependent suppression of insulin release. This effect was partly reverse...

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Vydáno v:J Clin Invest
Hlavní autoři: Burr, Ian M., Marliss, Errol B., Stauffacher, Werner, Renold, Albert E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1971
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292083/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5090060/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106628
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