Facilitated DNA Search by Multidomain Transcription Factors: Cross Talk via a Flexible Linker

More than 70% of eukaryotic proteins are composed of multiple domains. However, most studies of the search for DNA focus on individual protein domains and do not consider potential cross talk within a multidomain transcription factor. In this study, the molecular features of the DNA search mechanism...

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Detalles Bibliográficos
Main Authors: Vuzman, Dana, Polonsky, Michal, Levy, Yaakov
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2010
Assuntos:
Protein
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920665/
https://ncbi.nlm.nih.gov/pubmed/20713004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.007
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