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Obstacles May Facilitate and Direct DNA Search by Proteins
DNA recognition by DNA-binding proteins (DBPs), which is a pivotal event in most gene regulatory processes, is often preceded by an extensive search for the correct site. A facilitated diffusion process in which a DBP combines three-dimensional diffusion in solution with one-dimensional sliding alon...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3647173/ https://ncbi.nlm.nih.gov/pubmed/23663847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.03.030 |
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