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Obstacles May Facilitate and Direct DNA Search by Proteins

DNA recognition by DNA-binding proteins (DBPs), which is a pivotal event in most gene regulatory processes, is often preceded by an extensive search for the correct site. A facilitated diffusion process in which a DBP combines three-dimensional diffusion in solution with one-dimensional sliding alon...

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Detalhes bibliográficos
Main Authors: Marcovitz, Amir, Levy, Yaakov
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647173/
https://ncbi.nlm.nih.gov/pubmed/23663847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.03.030
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