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Generalized Facilitated Diffusion Model for DNA-Binding Proteins with Search and Recognition States
Transcription factors (TFs) such as the lac repressor find their target sequence on DNA at remarkably high rates. In the established Berg-von Hippel model for this search process, the TF alternates between three-dimensional diffusion in the bulk solution and one-dimensional sliding along the DNA cha...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353100/ https://ncbi.nlm.nih.gov/pubmed/22677385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.008 |
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