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A Yeast Toxic Mutant of HET-s((218-289)) Prion Displays Alternative Intermediates of Amyloidogenesis

Amyloids are thought to be involved in various types of neurodegenerative disorders. Several kinds of intermediates, differing in morphology, size, and toxicity, have been identified in the multistep amyloidogenesis process. However, the mechanisms explaining amyloid toxicity remain unclear. We prev...

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Main Authors: Berthelot, Karine, Lecomte, Sophie, Géan, Julie, Immel, Françoise, Cullin, Christophe
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920664/
https://ncbi.nlm.nih.gov/pubmed/20713008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.015
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