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Heterogeneous Seeding of a Prion Structure by a Generic Amyloid Form of the Fungal Prion-forming Domain HET-s(218–289)

The fungal prion-forming domain HET-s(218–289) forms infectious amyloid fibrils at physiological pH that were shown by solid-state NMR to be assemblies of a two-rung β-solenoid structure. Under acidic conditions, HET-s(218–289) has been shown to form amyloid fibrils that have very low infectivity in...

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Bibliografiset tiedot
Päätekijät: Wan, William, Bian, Wen, McDonald, Michele, Kijac, Aleksandra, Wemmer, David E., Stubbs, Gerald
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795258/
https://ncbi.nlm.nih.gov/pubmed/23986444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.505511
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