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A Yeast Toxic Mutant of HET-s((218-289)) Prion Displays Alternative Intermediates of Amyloidogenesis

Amyloids are thought to be involved in various types of neurodegenerative disorders. Several kinds of intermediates, differing in morphology, size, and toxicity, have been identified in the multistep amyloidogenesis process. However, the mechanisms explaining amyloid toxicity remain unclear. We prev...

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Detalhes bibliográficos
Main Authors: Berthelot, Karine, Lecomte, Sophie, Géan, Julie, Immel, Françoise, Cullin, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920664/
https://ncbi.nlm.nih.gov/pubmed/20713008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.015
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