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A Yeast Toxic Mutant of HET-s((218-289)) Prion Displays Alternative Intermediates of Amyloidogenesis

Amyloids are thought to be involved in various types of neurodegenerative disorders. Several kinds of intermediates, differing in morphology, size, and toxicity, have been identified in the multistep amyloidogenesis process. However, the mechanisms explaining amyloid toxicity remain unclear. We prev...

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Hlavní autoři: Berthelot, Karine, Lecomte, Sophie, Géan, Julie, Immel, Françoise, Cullin, Christophe
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920664/
https://ncbi.nlm.nih.gov/pubmed/20713008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.015
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