Mitochondrial Free [Ca(2+)] Increases during ATP/ADP Antiport and ADP Phosphorylation: Exploration of Mechanisms

ADP influx and ADP phosphorylation may alter mitochondrial free [Ca(2+)] ([Ca(2+)](m)) and consequently mitochondrial bioenergetics by several postulated mechanisms. We tested how [Ca(2+)](m) is affected by H(2)PO(4)(−) (P(i)), Mg(2+), calcium uniporter activity, matrix volume changes, and the bioen...

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Autori principali: Haumann, Johan, Dash, Ranjan K., Stowe, David F., Boelens, Age D., Beard, Daniel A., Camara, Amadou K.S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2010
Soggetti:
Biological Systems and Multicellular Dynamics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920628/
https://ncbi.nlm.nih.gov/pubmed/20712982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.069
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