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Slow Ca(2+) Efflux by Ca(2+)/H(+) Exchange in Cardiac Mitochondria Is Modulated by Ca(2+) Re-uptake via MCU, Extra-Mitochondrial pH, and H(+) Pumping by F(O)F(1)-ATPase
Mitochondrial (m) Ca(2+) influx is largely dependent on membrane potential (ΔΨ(m)), whereas mCa(2+) efflux occurs primarily via Ca(2+) ion exchangers. We probed the kinetics of Ca(2+)/H(+) exchange (CHE(m)) in guinea pig cardiac muscle mitochondria. We tested if net mCa(2+) flux is altered during a...
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| Publicado no: | Front Physiol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6378946/ https://ncbi.nlm.nih.gov/pubmed/30804812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01914 |
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