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Enhanced charge-independent mitochondrial free Ca(2+) and attenuated ADP-induced NADH oxidation by isoflurane: implications for cardioprotection

Modulation of mitochondrial free Ca(2+) ([Ca(2+)](m)) is implicated as one of the possible upstream factors that initiates anesthetic-mediated cardioprotection against ischemia-reperfusion (IR) injury. To unravel possible mechanisms by which volatile anesthetics modulate [Ca(2+)](m) and mitochondria...

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Detalhes bibliográficos
Main Authors: Agarwal, Bhawana, Camara, Amadou K.S., Stowe, David F., Bosnjak, Zeljko J., Dash, Ranjan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269543/
https://ncbi.nlm.nih.gov/pubmed/22155157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2011.11.011
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