Llwytho...

Pancreatic cancer DNMT1 expression and sensitivity to DNMT1 inhibitors

DNA methyltransferase I (DNMT1) is the major methyltransferase responsible for methylating DNA and is overexpressed in many cancers. DNMT1 is also a therapeutic target for chemotherapy and chemoprevention. We hypothesized that loss of DNMT1 copy number could result in reduced DNMT1 levels and greate...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Ang, Omura, Noriyuki, Hong, Seung-Mo, Goggins, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920347/
https://ncbi.nlm.nih.gov/pubmed/20234167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.9.4.10750
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