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Pancreatic cancer DNMT1 expression and sensitivity to DNMT1 inhibitors
DNA methyltransferase I (DNMT1) is the major methyltransferase responsible for methylating DNA and is overexpressed in many cancers. DNMT1 is also a therapeutic target for chemotherapy and chemoprevention. We hypothesized that loss of DNMT1 copy number could result in reduced DNMT1 levels and greate...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920347/ https://ncbi.nlm.nih.gov/pubmed/20234167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.9.4.10750 |
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