Unlike Pancreatic Cancer Cells Pancreatic Cancer Associated Fibroblasts Display Minimal Gene Induction after 5-Aza-2′-Deoxycytidine

PURPOSE: Cancer associated stromal fibroblasts (CAFs) undergo transcriptional and phenotypic changes that contribute to tumor progression, but the mechanisms responsible for these changes are not well understood. Aberrant DNA methylation is an important cause of transcriptional alterations in cancer...

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Autori principali: Yu, Jun, Walter, Kimberly, Omura, Noriyuki, Hong, Seung-Mo, Young, Angela, Li, Ang, Vincent, Audrey, Goggins, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439436/
https://ncbi.nlm.nih.gov/pubmed/22984426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043456
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