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Unlike Pancreatic Cancer Cells Pancreatic Cancer Associated Fibroblasts Display Minimal Gene Induction after 5-Aza-2′-Deoxycytidine

PURPOSE: Cancer associated stromal fibroblasts (CAFs) undergo transcriptional and phenotypic changes that contribute to tumor progression, but the mechanisms responsible for these changes are not well understood. Aberrant DNA methylation is an important cause of transcriptional alterations in cancer...

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Detaylı Bibliyografya
Asıl Yazarlar: Yu, Jun, Walter, Kimberly, Omura, Noriyuki, Hong, Seung-Mo, Young, Angela, Li, Ang, Vincent, Audrey, Goggins, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439436/
https://ncbi.nlm.nih.gov/pubmed/22984426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043456
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