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Structure of bacterial LigD 3′-phosphoesterase unveils a DNA repair superfamily

The DNA ligase D (LigD) 3′-phosphoesterase (PE) module is a conserved component of the bacterial nonhomologous end-joining (NHEJ) apparatus that performs 3′ end-healing reactions at DNA double-strand breaks. Here we report the 1.9 Å crystal structure of Pseudomonas aeruginosa PE, which reveals that...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nair, Pravin A., Smith, Paul, Shuman, Stewart
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919965/
https://ncbi.nlm.nih.gov/pubmed/20616014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005830107
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