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Structure of bacterial LigD 3′-phosphoesterase unveils a DNA repair superfamily
The DNA ligase D (LigD) 3′-phosphoesterase (PE) module is a conserved component of the bacterial nonhomologous end-joining (NHEJ) apparatus that performs 3′ end-healing reactions at DNA double-strand breaks. Here we report the 1.9 Å crystal structure of Pseudomonas aeruginosa PE, which reveals that...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919965/ https://ncbi.nlm.nih.gov/pubmed/20616014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005830107 |
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