Solution structure and DNA-binding properties of the phosphoesterase domain of DNA ligase D

The phosphoesterase (PE) domain of the bacterial DNA repair enzyme LigD possesses distinctive manganese-dependent 3′-phosphomonoesterase and 3′-phosphodiesterase activities. PE exemplifies a new family of DNA end-healing enzymes found in all phylogenetic domains. Here, we determined the structure of...

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Bibliographic Details
Main Authors: Natarajan, Aswin, Dutta, Kaushik, Temel, Deniz B., Nair, Pravin A., Shuman, Stewart, Ghose, Ranajeet
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3300020/
https://ncbi.nlm.nih.gov/pubmed/22084199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr950
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