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Solution NMR Studies of Chlorella Virus DNA Ligase-Adenylate
DNA ligases are essential guardians of genome integrity by virtue of their ability to recognize and seal 3′-OH/5′-phosphate nicks in duplex DNA. The substrate binding and three chemical steps of the ligation pathway are coupled to global and local changes in ligase structure, involving both massive...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2813346/ https://ncbi.nlm.nih.gov/pubmed/19913033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.11.007 |
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