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Solution NMR Studies of Chlorella Virus DNA Ligase-Adenylate

DNA ligases are essential guardians of genome integrity by virtue of their ability to recognize and seal 3′-OH/5′-phosphate nicks in duplex DNA. The substrate binding and three chemical steps of the ligation pathway are coupled to global and local changes in ligase structure, involving both massive...

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Bibliografiska uppgifter
Huvudupphovsmän: Piserchio, Andrea, Nair, Pravin A., Shuman, Stewart, Ghose, Ranajeet
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813346/
https://ncbi.nlm.nih.gov/pubmed/19913033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.11.007
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