Structures and activities of archaeal members of the LigD 3′-phosphoesterase DNA repair enzyme superfamily

LigD 3′-phosphoesterase (PE) is a component of the bacterial NHEJ apparatus that performs 3′-end-healing reactions at DNA breaks. The tertiary structure, active site and substrate specificity of bacterial PE are unique vis–à-vis other end-healing enzymes. PE homologs are present in archaea, but thei...

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Detaylı Bibliyografya
Asıl Yazarlar: Smith, Paul, Nair, Pravin A., Das, Ushati, Zhu, Hui, Shuman, Stewart
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2011
Konular:
Nucleic Acid Enzymes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082917/
https://ncbi.nlm.nih.gov/pubmed/21208981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1163
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