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Fas-associated death domain (FADD) is a negative regulator of T-cell receptor–mediated necroptosis
Cell death is an important mechanism to limit uncontrolled T-cell expansion during immune responses. Given the role of death-receptor adapter protein Fas-associated death domain (FADD) in apoptosis, it is intriguing that T-cell receptor (TCR)–induced proliferation is blocked in FADD-defective T cell...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919948/ https://ncbi.nlm.nih.gov/pubmed/20615958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005997107 |
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