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A New Element within the T-Cell Receptor α Locus Required for Tissue-Specific Locus Control Region Activity

Locus control regions (LCRs) are cis-acting regulatory elements thought to provide a tissue-specific open chromatin domain for genes to which they are linked. The gene for T-cell receptor α chain (TCRα) is exclusively expressed in T cells, and the chromatin at its locus displays differentially open...

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Detalhes bibliográficos
Main Authors: Ortiz, Benjamin D., Cado, Dragana, Winoto, Astar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC83983/
https://ncbi.nlm.nih.gov/pubmed/10022877
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