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Long-range looping of a locus control region drives tissue-specific chromatin packing within a multigene cluster

The relationships of higher order chromatin organization to mammalian gene expression remain incompletely defined. The human Growth Hormone (hGH) multigene cluster contains five gene paralogs. These genes are selectively activated in either the pituitary or the placenta by distinct components of a r...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Tsai, Yu-Cheng, Cooke, Nancy E., Liebhaber, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889918/
https://ncbi.nlm.nih.gov/pubmed/26893355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw090
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