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Long-range looping of a locus control region drives tissue-specific chromatin packing within a multigene cluster

The relationships of higher order chromatin organization to mammalian gene expression remain incompletely defined. The human Growth Hormone (hGH) multigene cluster contains five gene paralogs. These genes are selectively activated in either the pituitary or the placenta by distinct components of a r...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Tsai, Yu-Cheng, Cooke, Nancy E., Liebhaber, Stephen A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889918/
https://ncbi.nlm.nih.gov/pubmed/26893355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw090
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