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Long-range looping of a locus control region drives tissue-specific chromatin packing within a multigene cluster

The relationships of higher order chromatin organization to mammalian gene expression remain incompletely defined. The human Growth Hormone (hGH) multigene cluster contains five gene paralogs. These genes are selectively activated in either the pituitary or the placenta by distinct components of a r...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Tsai, Yu-Cheng, Cooke, Nancy E., Liebhaber, Stephen A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889918/
https://ncbi.nlm.nih.gov/pubmed/26893355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw090
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