Single-Molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations

The detection of single protein molecules1,2 in blood could help identify many new diagnostic protein markers. We report an approach for detecting hundreds to thousands of individual protein molecules simultaneously that enables the detection of very low concentrations of proteins. Proteins are capt...

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Detalhes bibliográficos
Main Authors: Rissin, David M., Kan, Cheuk W., Campbell, Todd G., Howes, Stuart C., Fournier, David R., Song, Linan, Piech, Tomasz, Patel, Purvish P., Chang, Lei, Rivnak, Andrew J., Ferrell, Evan P., Randall, Jeffrey D., Provuncher, Gail K., Walt, David R., Duffy, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919230/
https://ncbi.nlm.nih.gov/pubmed/20495550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1641
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