Development and Validation of Digital Enzyme-Linked Immunosorbent Assays for Ultrasensitive Detection and Quantification of Clostridium difficile Toxins in Stool

The currently available diagnostics for Clostridium difficile infection (CDI) have major limitations. Despite mounting evidence that toxin detection is paramount for diagnosis, conventional toxin immunoassays are insufficiently sensitive and cytotoxicity assays too complex; assays that detect toxige...

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Bibliografiske detaljer
Udgivet i:J Clin Microbiol
Main Authors: Song, Linan, Zhao, Mingwei, Duffy, David C., Hansen, Joshua, Shields, Kelsey, Wungjiranirun, Manida, Chen, Xinhua, Xu, Hua, Leffler, Daniel A., Sambol, Susan P., Gerding, Dale N., Kelly, Ciarán P., Pollock, Nira R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Bacteriology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572538/
https://ncbi.nlm.nih.gov/pubmed/26202120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01334-15
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