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LXR signaling pathways and atherosclerosis

First discovered as orphan receptors, liver X receptors (LXRs) were subsequently identified as the nuclear receptor target of the cholesterol metabolites, oxysterols.1 There are 2 LXR receptors encoded by distinct genes: LXRα is most highly expressed in the liver, adipose, kidney, adrenal tissues an...

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Dettagli Bibliografici
Autori principali: Calkin, Anna, Tontonoz, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919217/
https://ncbi.nlm.nih.gov/pubmed/20631351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.191197
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