TLR/MyD88 and LXRα Signaling Pathways Reciprocally Control Chlamydia Pneumoniae-Induced Acceleration of Atherosclerosis

Experimental and clinical studies link Chlamydia pneumoniae infection to atherogenesis and athero-thrombotic events, but the underlying mechanisms are unclear. We tested the hypothesis that C. pneumoniae-induced acceleration of atherosclerosis in ApoE(−/−) mice is reciprocally modulated by activatio...

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Main Authors: Naiki, Yoshikazu, Sorrentino, Rosalinda, Wong, Michelle H., Michelsen, Kathrin S., Shimada, Kenichi, Chen, Shuang, Yilmaz, Atilla, Slepenkin, Anatoly, Schröder, Nicolas W. J., Crother, Timothy R., Bulut, Yonca, Doherty, Terence M., Bradley, Michelle, Shaposhnik, Zory, Peterson, Ellena M., Tontonoz, Peter, Shah, Prediman K., Arditi, Moshe
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683843/
https://ncbi.nlm.nih.gov/pubmed/18981139
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