Chlamydia pneumoniae-Induced Foam Cell Formation Requires MyD88 Dependent and Independent Signaling and is Reciprocally Modulated by LXR Activation

Chlamydia pneumoniae is detected by macrophages and other antigen presenting cells via Toll-like receptors (TLRs), and can exacerbate developing atherosclerotic lesions, but how that occurs is not known. Liver X receptors (LXRs) centrally control reverse cholesterol transport, but also negatively mo...

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Detalhes bibliográficos
Main Authors: Chen, Shuang, Sorrentino, Rosalinda, Shimada, Kenichi, Bulut, Yonca, Doherty, Terence M., Crother, Timothy R., Arditi, Moshe
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662697/
https://ncbi.nlm.nih.gov/pubmed/18981140
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