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Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR

Nuclear receptors are integrators of hormonal and nutritional signals, mediating changes to metabolic pathways within the body. Given that modulation of lipid and glucose metabolism has been linked to diseases including type 2 diabetes, obesity and atherosclerosis, a greater understanding of pathway...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Calkin, Anna C., Tontonoz, Peter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597092/
https://ncbi.nlm.nih.gov/pubmed/22414897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3312
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