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Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR
Nuclear receptors are integrators of hormonal and nutritional signals, mediating changes to metabolic pathways within the body. Given that modulation of lipid and glucose metabolism has been linked to diseases including type 2 diabetes, obesity and atherosclerosis, a greater understanding of pathway...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597092/ https://ncbi.nlm.nih.gov/pubmed/22414897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3312 |
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