Transcriptional Regulation of Metabolic Pathways via Lipid-Sensing Nuclear Receptors PPARs, FXR, and LXR in NASH

Nonalcoholic fatty liver disease comprises a wide spectrum of liver injuries from simple steatosis to steatohepatitis and cirrhosis. Nonalcoholic steatohepatitis (NASH) is defined when liver steatosis is associated with inflammation, hepatocyte damage, and fibrosis. A genetic predisposition and envi...

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Publicado en:Cell Mol Gastroenterol Hepatol
Autores principales: Cariello, Marica, Piccinin, Elena, Moschetta, Antonio
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042405/
https://ncbi.nlm.nih.gov/pubmed/33545430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2021.01.012
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