The Role of Lipid Sensing Nuclear Receptors (PPARs and LXR) and Metabolic Lipases in Obesity, Diabetes and NAFLD

Obesity and type 2 diabetes mellitus (T2DM) are metabolic disorders characterized by metabolic inflexibility with multiple pathological organ manifestations, including non-alcoholic fatty liver disease (NAFLD). Nuclear receptors are ligand-dependent transcription factors with a multifaceted role in...

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Bibliographic Details
Published in:Genes (Basel)
Main Authors: Dixon, Emmanuel D., Nardo, Alexander D., Claudel, Thierry, Trauner, Michael
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145571/
https://ncbi.nlm.nih.gov/pubmed/33926085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12050645
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